DocumentCode :
2721465
Title :
Does the combination of magnetic resonance imaging and spectroscopic imaging improve the classification of brain tumours?
Author :
Devos, A. ; Lukas, L. ; Simonetti, A.W. ; Suykens, J.A.K. ; Vanhamme, L. ; van der Graaf, M. ; Buydens, L.M.C. ; Heerschap, A. ; Van Huffel, S.
Author_Institution :
Dept. of Electr. Eng., Katholieke Univ., Leuven, Belgium
Volume :
1
fYear :
2004
fDate :
1-5 Sept. 2004
Firstpage :
407
Lastpage :
410
Abstract :
Magnetic resonance imaging (MRI) and magnetic resonance spectroscopic imaging (MRSI) play an important role in the noninvasive diagnosis of brain tumours. We investigate the use of both MRI and MRSI, separately and in combination with each other for classification of brain tissue types. Many clinically relevant classification problems are considered; for example healthy versus tumour tissues, low- versus high-grade tumours. Linear as well as nonlinear techniques are compared. The classification performance is evaluated by the area under the receiver operating characteristic (ROC) curve (AUC). In general, all techniques achieve a high performance, except when using MRI alone. For example, for low- versus high-grade tumours, low- versus high-grade gliomas, gliomas versus meningiomas, respectively a test AUC higher than 0.91, 0.93 and 0.98 is reached, when both MRI and MRSI data are used.
Keywords :
biomedical MRI; brain; cancer; image classification; medical image processing; sensitivity analysis; tumours; brain tissue types; brain tumour classification; high-grade gliomas; high-grade tumours; low-grade gliomas; low-grade tumours; magnetic resonance imaging; magnetic resonance spectroscopic imaging; meningiomas; noninvasive diagnosis; receiver operating characteristic; Biomedical imaging; Biopsy; Brain; Linear discriminant analysis; Magnetic resonance; Magnetic resonance imaging; Noninvasive treatment; Spectroscopy; Testing; Tumors; Classification; Least Squares Support Vector Machine (LS-SVM); Linear Discriminant Analysis (LDA); Magnetic Resonance Imaging (MRI); Magnetic Resonance Spectroscopic Imaging (MRSI); brain tumours;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
Type :
conf
DOI :
10.1109/IEMBS.2004.1403180
Filename :
1403180
Link To Document :
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