Title :
High intensity focused ultrasound (HIFU) for the treatment of rectal tumors: a feasibility study
Author :
Sanghvi, N.T. ; Hawes, R. ; Kopecky, K. ; Gress, F. ; Ikenberry, S. ; Cummings, O. ; Zaidi, S. ; Hennige, C.
fDate :
Oct. 31 1994-Nov. 3 1994
Abstract :
A rigid ultrasound probe is under development for combined imaging and ablation of rectal tumors with high intensity focused ultrasound (HIFU). To test the device and to assess safety and efficacy of this technology, a canine model was developed by inducing rectal pseudotumors. These animals were imaged by ultrasound and treated with HIFU. The gross pathology and microscopic histology examinations were performed to establish performance of the device. It was observed that HIFU is capable of ablating the tumor tissue while sparing the rectal wall layers and normal surrounding tissue
Keywords :
acoustic focusing; acoustic intensity; biological effects of acoustic radiation; biomedical ultrasonics; radiation therapy; ultrasonic focusing; ultrasonic transducers; HIFU; ablation; animals; canine model; combined imaging; efficacy; feasibility study; high intensity focused ultrasound; microscopic histology; normal surrounding tissue; pathology; rectal pseudotumors; rectal tumor treatment; rectal wall layers; rigid ultrasound probe; safety; Ablation; Acoustic beam focusing; Animals; Biological effects of acoustic radiation; Biomedical applications of acoustic radiation; Biomedical transducers; Tumors;
Conference_Titel :
Ultrasonics Symposium, 1994. Proceedings., 1994 IEEE
Conference_Location :
Cannes, France
Print_ISBN :
0-7803-2012-3
DOI :
10.1109/ULTSYM.1994.401961
