Sorting and direct transportation of target molecules by bio-molecular selectivity and motor function

A bio-hybrid microsystem for sorting and carrying target molecules by bio-functional molecules is presented. Different target molecules, biotin-4-fluorescein and Rabbit anti-mouse IgG labeled with Alexa Fluor 568, were selectively attached on different beads (Streptavidin-coated and protein A-coated beads). Target molecules were separately transported by a motor protein system (kinesin on beads / microtubules on chip) without any liquid manipulation proving the feasibility of multiple target molecules on multiple beads sorter.