Title :
Image analysis of gated cardiac PET to assess left ventricular volumes and contractile function
Author :
Khorsand, A. ; Graf, S. ; Pirich, Ch ; Wagner, G. ; Moertl, D. ; Frank, H. ; Kletter, K. ; Sochor, H. ; Maurer, G. ; Schuster, E. ; Porenta, G.
Author_Institution :
Dept. of Cardiology, Wien Univ., Austria
Abstract :
The purpose of this study was to develop and validate PET image analysis tools that permit calculation of diastolic and systolic cardiac volumes and of LV ejection fraction from gated cardiac PET images. LV diameter and wall thickness were estimated by model based-fitting along radial rays obtained in short axis images. Endocardial contours and areas were derived from these estimates for a set of short axis images and LV volume was calculated. In a pilot study with 5 patients, results of obtained by the PET analysis tools were significantly correlated with measurements obtained by cardiac MRI imaging. (Vol-PET=0.89 Vol-MRI+14, r=0.94, p<0.0001; EF-PET=0.9I EF-MRI-1.42, R=0.98, p<0.005). Thus, model-based analysis of gated cardiac PET images seems to offer a novel capability for a near simultaneous assessment of myocardial perfusion, metabolism and contractile function
Keywords :
medical image processing; positron emission tomography; volume measurement; LV diameter; LV ejection fraction; cardiac MRI imaging; contractile function; diastolic cardiac volumes; endocardial areas; endocardial contours; gated cardiac PET image analysis; left ventricular volumes; medical diagnostic imaging; model based-fitting; nuclear medicine; radial rays; short axis images; systolic cardiac volumes; wall thickness; Biochemistry; Equations; Image analysis; Image reconstruction; Image resolution; Magnetic resonance imaging; Mathematical model; Myocardium; Positron emission tomography; Sugar;
Conference_Titel :
Computers in Cardiology 2000
Conference_Location :
Cambridge, MA
Print_ISBN :
0-7803-6557-7
DOI :
10.1109/CIC.2000.898519
