Image analysis of gated cardiac PET to assess left ventricular volumes and contractile function

Author

Khorsand, A. ; Graf, S. ; Pirich, Ch ; Wagner, G. ; Moertl, D. ; Frank, H. ; Kletter, K. ; Sochor, H. ; Maurer, G. ; Schuster, E. ; Porenta, G.

Author_Institution

Dept. of Cardiology, Wien Univ., Austria

fYear

2000

fDate

2000

Firstpage

311

Lastpage

314

Abstract

The purpose of this study was to develop and validate PET image analysis tools that permit calculation of diastolic and systolic cardiac volumes and of LV ejection fraction from gated cardiac PET images. LV diameter and wall thickness were estimated by model based-fitting along radial rays obtained in short axis images. Endocardial contours and areas were derived from these estimates for a set of short axis images and LV volume was calculated. In a pilot study with 5 patients, results of obtained by the PET analysis tools were significantly correlated with measurements obtained by cardiac MRI imaging. (Vol-PET=0.89 Vol-MRI+14, r=0.94, p<0.0001; EF-PET=0.9I EF-MRI-1.42, R=0.98, p<0.005). Thus, model-based analysis of gated cardiac PET images seems to offer a novel capability for a near simultaneous assessment of myocardial perfusion, metabolism and contractile function

Keywords

medical image processing; positron emission tomography; volume measurement; LV diameter; LV ejection fraction; cardiac MRI imaging; contractile function; diastolic cardiac volumes; endocardial areas; endocardial contours; gated cardiac PET image analysis; left ventricular volumes; medical diagnostic imaging; model based-fitting; nuclear medicine; radial rays; short axis images; systolic cardiac volumes; wall thickness; Biochemistry; Equations; Image analysis; Image reconstruction; Image resolution; Magnetic resonance imaging; Mathematical model; Myocardium; Positron emission tomography; Sugar;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 2000

Conference_Location

Cambridge, MA

ISSN

0276-6547

Print_ISBN

0-7803-6557-7

Type

conf

DOI

10.1109/CIC.2000.898519

Filename

898519