Title :
Silk-carbon nanotube composite for stem cell neuronal differentiation
Author :
Chen, Chi-Shuo ; Le, Catherine ; Soni, Sushant ; Chen, Eric Y-T ; Chin, Wei-Chun
Author_Institution :
Bioeng., Univ. of California, Merced, Merced, CA, USA
Abstract :
This study aims to create a new paradigm for building 3D silk-carbon nanotube (CNT) based composite scaffolds in order to acquire better neuron differentiation efficiency from human embryonic stem cells (hESCs). CNT and silk have been successfully used for neuronal differentiation and tissue engineering applications. The silk-CNT composite scaffolds can serve as efficient support matrices for stem cell derived neuronal transplants that offer a promising opportunity for nerve injury treatments in spinal cord injury (SCI) patients.
Keywords :
biomedical materials; carbon nanotubes; cellular biophysics; nanocomposites; nanomedicine; neurophysiology; tissue engineering; 3D silk-carbon nanotube composite; C; composite scaffold; human embryonic stem cells; nerve injury treatment; neuron differentiation efficiency; spinal cord injury; stem cell neuronal differentiation; tissue engineering; Fluorescence; Humans; Nerve fibers; Stem cells; Substrates; Tissue engineering; carbon nanotube; neuron and differentiation; silk; stem cell;
Conference_Titel :
Nanoelectronics Conference (INEC), 2011 IEEE 4th International
Conference_Location :
Tao-Yuan
Print_ISBN :
978-1-4577-0379-9
Electronic_ISBN :
2159-3523
DOI :
10.1109/INEC.2011.5991795
