Time-division self-referencing multichannel spectral SPR sensor without mechanical scanning

A multichannel spectral surface plasmon resonance (SPR) sensor module which provides self-referencing capability has been designed to inhibit error influences arising from light source instability. The device timely refreshes the light intensity baseline based on periodical scans over several channels. In particular, the scan operation is achieved by changing optical media on the optical path instead of conventional mechanical scanning. Experiments demonstrate that the sensor module achieves a refractive index resolution level up to ~9.3×10^-7 RIU.