3D microprobes for deep brain stimulation and recording

A new generation of three dimensional (3D) multi channel microprobes is reported for deep brain stimulation (DBS) applications offering both stimulation and recording capabilities. The devices are comprised of planar flexible microprobes assembled or folded over cylindrical polyurethane shafts with radiuses as low as 350 μm. As a direct benefit of this approach, the dimensions and density of the electrode sites are precisely defined by the sub-micrometer resolution of the lithography processes employed for fabrication of planar devices. This work presents a microprobe with 16 stimulating and 16 recording channels. The stimulation sites are 100 μm × 1.5 mm while the recording sites are 20 μm × 20 μm.