DocumentCode
2925946
Title
Spike detection in extracellular recordings by hybrid blind beamforming
Author
Natora, Michal ; Franke, Felix ; Obermayer, Klaus
Author_Institution
Inst. for Software Eng. & Theor. Comput. Sci., Berlin Inst. of Technol., Berlin, Germany
fYear
2010
fDate
Aug. 31 2010-Sept. 4 2010
Firstpage
4636
Lastpage
4641
Abstract
In the case of extracellular recordings, spike detection algorithms are necessary in order to retrieve information about neuronal activity form the data. We present a new spike detection algorithm which is based on methods from the field of blind equalization and beamforming. In contrast to existing approaches, our method estimates several waveforms directly from the data and corresponding linear filters are constructed. The estimation is done in an unsupervised manner, and the few parameters of the algorithm are intuitive to set. The algorithm allows for superior detection performance, even when multiple neurons with various waveforms are present in the data. We compare our method with current state-of-the-art spike detection algorithms, and show that the proposed method achieves favorable results.
Keywords
blind equalisers; cellular biophysics; medical signal detection; neurophysiology; parameter estimation; blind equalization; extracellular recordings; hybrid blind beamforming; linear filters; neuronal activity; spike detection; Blind equalizers; Detection algorithms; Estimation; Kernel; Neurons; Signal to noise ratio; Action Potentials; Algorithms; Diagnosis, Computer-Assisted; Electrodiagnosis; Humans; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location
Buenos Aires
ISSN
1557-170X
Print_ISBN
978-1-4244-4123-5
Type
conf
DOI
10.1109/IEMBS.2010.5626483
Filename
5626483
Link To Document