• DocumentCode
    2925946
  • Title

    Spike detection in extracellular recordings by hybrid blind beamforming

  • Author

    Natora, Michal ; Franke, Felix ; Obermayer, Klaus

  • Author_Institution
    Inst. for Software Eng. & Theor. Comput. Sci., Berlin Inst. of Technol., Berlin, Germany
  • fYear
    2010
  • fDate
    Aug. 31 2010-Sept. 4 2010
  • Firstpage
    4636
  • Lastpage
    4641
  • Abstract
    In the case of extracellular recordings, spike detection algorithms are necessary in order to retrieve information about neuronal activity form the data. We present a new spike detection algorithm which is based on methods from the field of blind equalization and beamforming. In contrast to existing approaches, our method estimates several waveforms directly from the data and corresponding linear filters are constructed. The estimation is done in an unsupervised manner, and the few parameters of the algorithm are intuitive to set. The algorithm allows for superior detection performance, even when multiple neurons with various waveforms are present in the data. We compare our method with current state-of-the-art spike detection algorithms, and show that the proposed method achieves favorable results.
  • Keywords
    blind equalisers; cellular biophysics; medical signal detection; neurophysiology; parameter estimation; blind equalization; extracellular recordings; hybrid blind beamforming; linear filters; neuronal activity; spike detection; Blind equalizers; Detection algorithms; Estimation; Kernel; Neurons; Signal to noise ratio; Action Potentials; Algorithms; Diagnosis, Computer-Assisted; Electrodiagnosis; Humans; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
  • Conference_Location
    Buenos Aires
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-4123-5
  • Type

    conf

  • DOI
    10.1109/IEMBS.2010.5626483
  • Filename
    5626483