• DocumentCode
    2928640
  • Title

    Submicron reflection confocal microscope with a multimode fiber output

  • Author

    Ilev, Ilko K. ; Waynant, Ronald

  • Author_Institution
    US Food & Drug Adm., Rockville, MD, USA
  • fYear
    2000
  • fDate
    7-12 May 2000
  • Firstpage
    503
  • Lastpage
    504
  • Abstract
    Summary form only given.Among modern optical imaging techniques, confocal microscopy has been extensively studied and applied to many practical fields ranging from biology to materials science. It provides sharp, high-magnification imaging of thick specimens by rejection of out-of-focus information. Further research efforts are focused on improvement the resolving power. Besides conventional pinhole-based confocal systems, a fiber-optic approach is also applied to improve the spatial resolution. In this case, the light efficiency is lower because small-core single-mode fibers are basically used for pinhole detection. Moreover, a reflection-type confocal microscope represents an attractive confocal configuration for axial resolution improvement.
  • Keywords
    optical fibres; optical focusing; optical microscopes; optical resolving power; axial resolution improvement; confocal microscopy; fiber-optic approach; high-magnification imaging; multimode fiber output; optical imaging techniques; out-of-focus information; pinhole detection; pinhole-based confocal systems; resolving power; small-core single-mode fibers; spatial resolution; submicron reflection confocal microscope; thick specimens; Fiber lasers; Fluorescence; Frequency domain analysis; Measurement techniques; Microscopy; Optical films; Optical reflection; Optimized production technology; Signal design; Signal resolution;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics, 2000. (CLEO 2000). Conference on
  • Conference_Location
    San Francisco, CA, USA
  • Print_ISBN
    1-55752-634-6
  • Type

    conf

  • DOI
    10.1109/CLEO.2000.907313
  • Filename
    907313