Title :
Submicron reflection confocal microscope with a multimode fiber output
Author :
Ilev, Ilko K. ; Waynant, Ronald
Author_Institution :
US Food & Drug Adm., Rockville, MD, USA
Abstract :
Summary form only given.Among modern optical imaging techniques, confocal microscopy has been extensively studied and applied to many practical fields ranging from biology to materials science. It provides sharp, high-magnification imaging of thick specimens by rejection of out-of-focus information. Further research efforts are focused on improvement the resolving power. Besides conventional pinhole-based confocal systems, a fiber-optic approach is also applied to improve the spatial resolution. In this case, the light efficiency is lower because small-core single-mode fibers are basically used for pinhole detection. Moreover, a reflection-type confocal microscope represents an attractive confocal configuration for axial resolution improvement.
Keywords :
optical fibres; optical focusing; optical microscopes; optical resolving power; axial resolution improvement; confocal microscopy; fiber-optic approach; high-magnification imaging; multimode fiber output; optical imaging techniques; out-of-focus information; pinhole detection; pinhole-based confocal systems; resolving power; small-core single-mode fibers; spatial resolution; submicron reflection confocal microscope; thick specimens; Fiber lasers; Fluorescence; Frequency domain analysis; Measurement techniques; Microscopy; Optical films; Optical reflection; Optimized production technology; Signal design; Signal resolution;
Conference_Titel :
Lasers and Electro-Optics, 2000. (CLEO 2000). Conference on
Conference_Location :
San Francisco, CA, USA
Print_ISBN :
1-55752-634-6
DOI :
10.1109/CLEO.2000.907313