Title :
Submicron-fabrication of bovine serum albumin (BSA) matrix via two-photon photochemical crosslinking
Author :
Xu, Jinye ; Cheng, Jinping ; Cheng, Shuk Han ; Chan, Barbara P.
Abstract :
We present the successful fabrication of bovine serum albumin matrix with novel two-photon photochemical crosslinking technique. Electron scanning microscope images revealed the highly porous microstructures of as-fabricated matrices. Dose dependence of the microstructures on both BSA and Rose Bengal has been studied. 2D patterns and 3D micropillars of BSA have also been fabricated, which potentially can be used as a model of cell-matrix study.
Keywords :
biomedical materials; materials preparation; microfabrication; photochemistry; polymers; porous materials; proteins; 2D BSA patterns; 3D BSA micropillars; BSA matrix submicron fabrication; Rose Bengal; bovine serum albumin; cell-matrix model; electron scanning microscopy; highly porous microstructures; two photon photochemical crosslinking; Fabrication; Mechanical factors; Microstructure; Proteins; Scanning electron microscopy; Three dimensional displays; micro-fabrication; multi-photon absortion; photochemial crosslinking;
Conference_Titel :
Nano/Molecular Medicine and Engineering (NANOMED), 2010 IEEE 4th International Conference on
Conference_Location :
Hong Kong/Macau
Print_ISBN :
978-1-61284-152-6
DOI :
10.1109/NANOMED.2010.5749821
