Title :
Identifying duplications and lateral gene transfers simultaneously and rapidly
Author :
Zhi-Zhong Chen ; Fei Deng ; Lusheng Wang
Author_Institution :
Dept. of Inf. Syst. Design, Tokyo Denki Univ., Tokyo, Japan
Abstract :
This paper deals with the problem of enumerating all minimum-cost LCA-reconciliations involving gene duplications and lateral gene transfers (LGTs) for a given species tree S and a given gene tree G. Previously, Tofigh et al. [20] gave a fixed-parameter algorithm for this problem that runs in O(m + 3k n) time, where m is the number of vertices in S, n is the number of vertices in G, and k is the minimum cost of an LCA-reconciliation between Sand G. In this paper, by refining their algorithm, we obtain a new one for the same problem that finds and outputs the solutions in a compact form within O(mn2 + 3k) time.
Keywords :
biology computing; evolution (biological); genetics; fixed-parameter algorithm; gene duplications; gene tree; lateral gene transfers; minimum-cost LCA-reconciliations; Binary trees; Bioinformatics; Computational biology; Educational institutions; Electronic mail; Junctions; Vegetation;
Conference_Titel :
Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 2013 IEEE Symposium on
Conference_Location :
Singapore
DOI :
10.1109/CIBCB.2013.6595398