Title :
An intraoperative brain-shift monitor using shear-mode transcranial ultrasound: Preliminary results
Author :
White, P.J. ; Whalen, S. ; Tang, S.C. ; Clement, G.T. ; Jolesz, F.A. ; Golby, A.J.
Author_Institution :
Brigham & Women´´s Hosp., Harvard Med. Sch., Boston, MA
Abstract :
A device that uses the shear mode of transcranial ultrasound transmission for intraoperative monitoring has been designed, constructed, and tested with 10 human subjects. Magnetic resonance (MR) images were obtained with the device spatially registered to the MR reference coordinates. Peaks in both the ultrasound and MR signals were identified and analyzed both for spatial localization and signal-to-noise ratio (SNR). The first results aimed towards validating the prototype device against MRI have demonstrated excellent correlation (n = 38, R2 = 0.9962) between the structural localization abilities of the two modalities. In addition, the overall SNR of the ultrasound backscatter signals (n = 38, SNR = 25.4plusmn5.2 dB) was statistically equivalent to that of the MR data (n = 38, SNR = 22.5plusmn4.8 dB).
Keywords :
biomedical MRI; biomedical ultrasonics; brain; neurophysiology; patient monitoring; surgery; MRI; intraoperative brain-shift monitor; magnetic resonance images; neurosurgery; shear-mode transcranial ultrasound; signal-to-noise ratio; spatial localization; structural localization; ultrasound backscatter signal; Humans; Magnetic analysis; Magnetic resonance; Monitoring; Prototypes; Signal analysis; Signal processing; Signal to noise ratio; Testing; Ultrasonic imaging; brain shift; monitor; neurosurgery; transcranial; ultrasound;
Conference_Titel :
Ultrasonics Symposium, 2008. IUS 2008. IEEE
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2428-3
Electronic_ISBN :
978-1-4244-2480-1
DOI :
10.1109/ULTSYM.2008.0330
