Title :
The Comparison of Haplotype Difference Based on the 21st Chromosome of Four Populations
Author :
Pei, Zhili ; Zhou, Yuxin ; Liu, Lisha ; Wang, Lihua ; Lu, Yinan ; Kong, Ying
Author_Institution :
Coll. of Comput. Sci. & Technol., Inner Mongolia Univ. for the Nationalites, Tongliao, China
Abstract :
Single nucleotide polymorphisms are the most plentiful genetic variations of human genome. Haplytype is a group of interrelated SNP allele loci, which are located at one chromosome or certain regions. It has been the important composition of human genetic research in recent years. In the research on complex disease, the analysis of haplotype composed by many SNP loci is superior to the analysis of one SNP locus. In this paper, through the processing of genotype data provided by Hapmap project, the haplotype data of 21st chromosome of four populations are obtained. The haplotype difference of four populations is also obtained by the reasonable comparing algorithms.
Keywords :
diseases; genetics; 21st chromosome; complex disease; haplotype difference; human genetic research; human genome; interrelated SNP allele loci; single nucleotide polymorphisms; Bioinformatics; Biological cells; DNA; Diseases; Genomics; Humans; Haplotype; SNPs; complex disease Introduction; infective genes;
Conference_Titel :
Electrical and Control Engineering (ICECE), 2010 International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-6880-5
DOI :
10.1109/iCECE.2010.561
