Analysis of airway pressure and flow by non linear electrical circuit system: optimized model

This study aims to clarify the effects of nonlinearity in the biological respiratory system and of nonlinear terms in the cost function to evaluate the performance and the optimality of the system. The increase in nonlinear resistive component elevated airway pressure and depressed airway flow. An intense minimization of the linear and nonlinear terms involving airway pressure depressed the rapid increase in airway pressure and the peak flow rate. They have the most potent effect on airway pressure and airway flow compared with any other terms. These nonlinear terms are necessary and indispensable to produce the physiological respiration