Title :
Detection of specific bioparticles using antibodies-coated gold nanoparticles and dielectrophoretic impedance measurement
Author :
Huang, Jung-Tang ; Yu, Hua-Wei ; Hou, Shao-Yi ; Fang, Shiuh-Bin ; Lee, Hung-Chan ; Yang, Chu-Zen
Author_Institution :
Department of Mechanical Engineering, National Taipei University of Technology, Taiwan ROC
Abstract :
In this study, we developed an easy and quick test capable of identifying specific bacteria in one hour. The protocol was established based on the measurement of bacteria quantity on a biochip with comb-like electrodes. Gold nanoparticles coated with anti-Salmonella antibody were used to enhance the dielectrophretic property of Salmonella spp. on the biochip to facilitate the sensitivity.
Keywords :
Dielectric measurements; Dielectrophoresis; Electrodes; Gold; Impedance measurement; Microorganisms; Nanoparticles; Pathogens; Permittivity; Testing; Algorithms; Antibodies; Biosensing Techniques; Electric Impedance; Electrochemistry; Electrodes; Gold; Humans; Metal Nanoparticles; Models, Statistical; Nanoparticles; Nanotechnology; Salmonella; Stem Cells; Time Factors;
Conference_Titel :
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location :
Vancouver, BC
Print_ISBN :
978-1-4244-1814-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2008.4649878
