Title :
A Cellular Automaton Model for the Transmission Dynamics of Schistosomiasis
Author :
Yun Liu ; Kai Chu ; Xiaoli Xu ; Haiwei Wu ; Cheng Wan
Author_Institution :
Dept. of Pathogen Biol., Nanjing Med. Univ., Nanjing, China
Abstract :
In this paper, a new stochastic model based on cellular automata is established to simulate the occurrence and development of Schistosoma japonicum (S. japonicum) infection in an endemic population. We included the process of the pathogen invasion from exposure to worm development and till worm death when the infection is cleared in the model. We further utilized the model to predict the prevalence as the outcomes of the selected chemotherapy carried out in Jiahu village. Comparing model predicted prevalence and intensities with the observed parameters, it is anticipated that our cellular automaton transmission model can serve as a tool for studying schistosomiasis transmission dynamics in endemic areas.
Keywords :
cellular biophysics; diseases; medical computing; patient treatment; physiological models; stochastic processes; Jiahu village; Schistosoma japonicum infection; cellular automaton model; chemotherapy; endemic areas; endemic population; pathogen invasion; schistosomiasis transmission dynamics; stochastic model; worm death; worm development; Automata; Biological system modeling; Differential equations; Diseases; Lakes; Mathematical model; Medical simulation; Pathogens; Predictive models; Stochastic processes;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
DOI :
10.1109/ICBBE.2010.5514785