DocumentCode :
3098705
Title :
An electronic microfluidic switch using dielectrophoresis for control of microparticles
Author :
Javanmard, Mehdi ; Emaminejad, Sam ; Dutton, Robert ; Davis, Ronald W.
Author_Institution :
Stanford Genome Technol. Center, Stanford Univ., Stanford, CA, USA
fYear :
2011
fDate :
7-9 Dec. 2011
Firstpage :
1
Lastpage :
1
Abstract :
By making use of the advantages offered by micro and nanotechnologies, we aim to develop technologies which will decrease cost, increase assay speed, and improve limit of detection in biomolecular assays. Increasing sensitivity can enable earlier detection, and also can allow for identification of low-abundance markers that are not detectable with current techniques. We have previously developed a microfluidic platform capable of detecting enzyme activity at the attomolar level [1]. In order to transform this technology into a high throughput multiplexed assay, while maintaining low cost, instead of using microfluidic valves which requires extensive tubing and external pumps, it is desirable to achieve fluidic control of microparticles electrically. Using modern VLSI techniques, routing of hundreds or even thousands of electrodes and interconnects on a silicon chip is trivial compared to the requirement of connecting hundreds of tubes to a fluidic chip, which can become a plumbers nightmare.
Keywords :
VLSI; biomolecular electronics; electrophoresis; microfluidics; nanotechnology; sensitivity analysis; silicon; VLSI technique; attomolar level; biomolecular assay; dielectrophoresis; electronic microfluidic switch; enzyme activity detection; fluidic chip; high throughput multiplexed assay; low-abundance marker; microparticle control; microparticle fluidic control; microtechnology; nanotechnology; silicon chip; Dielectrophoresis; Electrodes; Force; Immune system; Microfluidics; Multiplexing; Switches;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Semiconductor Device Research Symposium (ISDRS), 2011 International
Conference_Location :
College Park, MD
Print_ISBN :
978-1-4577-1755-0
Type :
conf
DOI :
10.1109/ISDRS.2011.6135210
Filename :
6135210
Link To Document :
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