Title :
Molecular engineering of sensors for biological materials
Author :
Lloyd, C. ; Mason, H.-Y. ; Sinclair, R. ; Estes, C. ; Duncan, A. ; Wade, B. ; Ellis, W. ; Powers, Jr L.
Author_Institution :
Nat. Center for the Design of Molecular Function, Utah State Univ., Logan, UT, USA
Abstract :
Molecular engineering methods have been used to develop sensors for the capture of DNA, viruses, and bacterial cells, spores, and toxins. The capture technology exploits the molecular basis of pathogenesis and capture events are detected using the intrinsic fluorescence of the captured microbial components. Capabilities include statistically sampling the environment in minutes and sensitivity of ∼100 cells/cm3.
Keywords :
DNA; biosensors; fluorescence; microorganisms; molecular biophysics; anthrax-tainted mail; bacterial cells; capture technology; diagnostic technologies; intrinsic fluorescence; microbial food contamination; pathogenesis; spores; statistically sampled environment; toxins; viruses; Biological materials; Biosensors; DNA; Event detection; Fluorescence; Fungi; Microorganisms; Pathogens; Sampling methods; Viruses (medical);
Conference_Titel :
Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on
Print_ISBN :
0-7803-7557-2
DOI :
10.1109/MCTE.2002.1174988
