Temperature Control in Mini-Bioreactor and Its Impact to Immunoassay

Author

Chang, Yaw-Jen ; Chen-Yang, Yui Whei ; Chen, Jun-Ying

Author_Institution

Dept. of Mech. Eng., Chung Yuan Christian Univ., Chungli, Taiwan

fYear

2010

fDate

18-20 June 2010

Firstpage

1

Lastpage

3

Abstract

In this paper, the precise temperature control incorporated in the mini-bioreactor for biochemical reaction was developed. The temperature control system can be operated from computer. The variation of temperature is within ± 0.2°C using fuzzy control algorithm. Compared with conventional oven, it has 10-fold precision. It also has better heating efficiency with rapid rising time to reach the desired temperature. The experimental results of immunoassays show that the temperature control has a great impact to immnuoreaction. Under a stable temperature environment, the variation of fluorescence intensities scanned after immunoassays is smaller for all titration concentrations. The temperature control system in mini-bioreactor can promote better experimental results of immunoassay.

Keywords

biochemistry; bioreactors; fluorescence; fuzzy control; temperature control; biochemical reaction; conventional oven; fluorescence intensities; fuzzy control algorithm; immnuoreaction; immunoassay; mini-bioreactor; temperature control; titration concentrations; Chemistry; Fluorescence; Fuzzy control; Humidity control; Immune system; Mechanical engineering; Ovens; Proteins; Temperature control; Temperature measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on

Conference_Location

Chengdu

ISSN

2151-7614

Print_ISBN

978-1-4244-4712-1

Electronic_ISBN

2151-7614

Type

conf

DOI

10.1109/ICBBE.2010.5516874

Filename

5516874