Title :
A Plasmon-controlled Fluorescence Biochip
Author :
Matthews, Daniel ; Summers, Huw ; Njoh, Kerenza ; Chappell, Sally ; Errington, Rachel ; Smith, Paul ; Pope, Iestyn ; Vojnovic, Boris ; Ameer-Beg, Simon
Author_Institution :
Sch. of Phys. & Astron., Cardiff University
Abstract :
In this paper, we report on the development of a fully integrated biochip that uses surface plasmons to control all aspects of a fluorescence assay. This includes both excitation and emission characteristics and so in addition to the fluorescence enhancement/quenching also control of the spatial location, beam direction and polarization of the excitation light. These effects are investigated with both bare fluorescent molecules and quantum dot-labeled cells
Keywords :
biosensors; cellular biophysics; fluorescence; molecular biophysics; optical control; optical sensors; quantum dots; radiation quenching; surface plasmons; emission characteristics; excitation light polarization; fluorescence quenching; fluorescent molecules; integrated biochip; plasmon-controlled fluorescence assay; quantum dot-labeled cells; surface plasmons; Corrugated surfaces; Fluorescence; Glass; Gold; Gratings; Laser beams; Laser excitation; Plasmons; Quantum dot lasers; Surface emitting lasers;
Conference_Titel :
Lasers and Electro-Optics Society, 2006. LEOS 2006. 19th Annual Meeting of the IEEE
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-9555-7
Electronic_ISBN :
0-7803-9555-7
DOI :
10.1109/LEOS.2006.278891
