Title :
Detecting Method of Quantitative Colloidal Gold Test Strip Concentration Based on the DSP Image Processing
Author :
Zheng Dezhi ; Wu Zongling ; Wang Shuai
Author_Institution :
Dept. of Instrum. Sci. & Opto-Electron. Eng., Beijing Univ. of Aeronaut. & Astronaut., Beijing, China
Abstract :
Immunogold labeling technique is mainly used on detecting of quantitative colloidal gold test strip concentration, through comparing with the color standard card to realize visual qualitative analysis, but the disadvantages are low measurement accuracy, high misjudgment rate, and it is difficult to achieve quantitative measurement. This paper adopts an embedded image processing system which based on the DSP. The image information of the quantitative colloidal gold test strip is sampled by the image sensor CMOS, analysis processed based on the image feature, fringe intensity image of feature information is extracted, and then establishes the functional relation between image feature information of fringe intensity and sample concentration, so it can realizes accurate measurement, and offers a detecting method to the colloidal gold qualitative detecting. In order to solve the problem that CMOS sensor generates drift follow with the working temperature, the system provides constant temperature working environment for the CMOS sensor and then solves the long-term stability problem of the system. Compared with other methods, it has advantages of high precision, fast inspection speed and so on. The results show that the method of quantitative detection of colloidal gold test strip concentration has upper applied value, which based on the DSP hardware platform, it precision can be up to ±5%, repeatability error reaches ±1%.
Keywords :
CMOS image sensors; chemical analysis; chemical sensors; colloids; gold; image processing; Au; CMOS image sensor; DSP image processing; color standard card; embedded image processing system; feature information; fringe intensity image; high precision fast inspection; image feature; immunogold labeling technique; measurement accuracy; misjudgment rate; qualitative analysis; quantitative colloidal gold test strip concentration; CMOS image sensors; Digital signal processing; Gold; Image color analysis; Image processing; Labeling; Sensor systems; Strips; Temperature sensors; Testing;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5517142