A Novel Giant DNA Transpson in Nematostella vectensis

Author

Chu, Peili ; Wang, Xingyun ; Hu, Jing ; Luo, Qin ; Zhou, Qingchun

Author_Institution

Hubei Key Lab. of Genetic Regul. & Integrative Biol., Huazhong Normal Univ., Wuhan, China

fYear

2010

fDate

18-20 June 2010

Firstpage

1

Lastpage

4

Abstract

With genome-wide screening of N. vectensis, two new groups of Polinton were identified, beside five Polinton groups deposited in Repbase. The typical N. vectensis Polinton is in length of 15-20kb and has long TIRs with a 6-bp TSDs. it encodes as many as 6 different proteins, including retroviral-like integrase (INT), adenovirus protease (PRO), DNA polymerase B (POLB) and putative ATPase (ATP). These ancient N. vectensis Polinton groups fall to two clades by phylogenetic analysis. One clade evolves evolves to vertebrates together with large scale gene linkage of N. vectensis, another clade following to the evolution of fly and nematode genome.

Keywords

DNA; biochemistry; cellular biophysics; enzymes; evolution (biological); genetics; genomics; proteomics; zoology; DNA polymerase B; N. vectensis Polinton; Nematostella vectensis; adenovirus protease; evolution; fly genome; genome-wide screening; giant DNA transpson; large scale gene linkage; nematode genome; phylogenetic analysis; proteins; putative ATPase; retroviral-like integrase; vertebrates; Biochemistry; Bioinformatics; DNA; Encoding; Genetics; Genomics; Phylogeny; Polymers; Proteins; Sequences;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on

Conference_Location

Chengdu

ISSN

2151-7614

Print_ISBN

978-1-4244-4712-1

Electronic_ISBN

2151-7614

Type

conf

DOI

10.1109/ICBBE.2010.5517337

Filename

5517337