Title :
Ultra Giant Vesicles out of a Planar Membrane
Author :
Funakoshi, Kei ; Suzuki, Hiroaki ; Takeuchi, Shoji
Author_Institution :
Inst. of Ind. Sci., Tokyo Univ.
Abstract :
We report a method for forming ultra giant lipid vesicles. A chip device with a micro-jet nozzle was fabricated. The vesicles were produced by applying pulsed micro jets to a planar lipid bilayer, analogous to blowing soap bubbles from a liquid film. Using this method, lipid vesicles with diameters of about 500 mum were formed one-by-one. This method enables the encapsulation of target molecules or nano particles into the vesicles rapidly and efficiently
Keywords :
biological techniques; biomembranes; cellular biophysics; jets; lab-on-a-chip; lipid bilayers; microfluidics; nozzles; artificial biofunctional membranes; chip device; lab on a chip; microcapsule; microjet nozzle; nano particle encapsulation; planar lipid bilayer; planar membrane; pulsed micro jets; target molecule encapsulation; ultra giant lipid vesicles formation; Biology; Biomembranes; Cells (biology); Drug delivery; Encapsulation; Fractionation; Glass; Lipidomics; Microfluidics; Substrates; Artificial biofunctional membranes; Lab on a chip; Micro capsule; Microjet device;
Conference_Titel :
Microtechnologies in Medicine and Biology, 2006 International Conference on
Conference_Location :
Okinawa
Print_ISBN :
1-4244-0338-3
Electronic_ISBN :
1-4244-0338-3
DOI :
10.1109/MMB.2006.251492
