DocumentCode :
3161776
Title :
An alternative index for monitoring microcirculatory blood flow: The beat-to-beat microcirculatory blood flow variability
Author :
Hsiu, Hsin ; Hsu, Wei-Chen ; Hsu, Chia Liang
Author_Institution :
Dept. of Electr. Eng., Yuan Ze Univ., Chungli, Taiwan
fYear :
2009
fDate :
2-4 Dec. 2009
Firstpage :
1
Lastpage :
4
Abstract :
Objective: Cardiovascular variability analysis, such heart rate variability or blood pressure variability, provides important information about activities of various regulatory mechanisms for the cardiovascular system. Aim of the present study is to use the laser Doppler flowmetry (LDF) measurement to study the correspondent changes between the beat-to-beat microcirculatory blood flow (MBF) and its variation (MBFV). Methods: 17 trials were performed on 5 male healthy volunteers. For each experiment, we applied local heating (LH) stimulation and recorded a 20-minute heating-effect data sequence. For each pulse, DCflux (average LDF flux) was calculated, and CV (coefficient of variation) of DCflux (DCCV) was then calculated to evaluate the beat-to-beat MBFV. Results: The slope between DCCV and DCflux was negative with R2 >0.7 (p<0.01 by F-test). Conclusion: Our results suggest that by providing an alternative solution to overcome the major drawback for LDF measurement of lacking quantitative evaluation, MBFV parameters calculated from the beat-to-beat LDF waveform may have meaning in improving the evaluation for the LH response of the MBF perfusion.
Keywords :
Doppler measurement; biomedical ultrasonics; cardiovascular system; haemodynamics; haemorheology; patient monitoring; MBF perfusion; alternative index; applied local heating stimulation; beat-to-beat LDF waveform; beat-to-beat microcirculatory blood flow variability; cardiovascular variability analysis; healthy volunteers; heating effect data sequence; laser Doppler flowmetry measurement; patient monitoring; time 20 min; Blood flow; Blood pressure variability; Cardiology; Cardiovascular system; Fluid flow measurement; Heart rate variability; Heating; Information analysis; Laser transitions; Monitoring;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical and Pharmaceutical Engineering, 2009. ICBPE '09. International Conference on
Conference_Location :
Singapore
Print_ISBN :
978-1-4244-4763-3
Electronic_ISBN :
978-1-4244-4764-0
Type :
conf
DOI :
10.1109/ICBPE.2009.5384107
Filename :
5384107
Link To Document :
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