DocumentCode :
3188119
Title :
Application of soft lithography to mechanobiology
Author :
Naruse, Keiji
Author_Institution :
Dept. of Cardiovascular Physiol., Okayama Univ. Graduate Sch. of Medicine, Japan
fYear :
2005
fDate :
7-9 Nov. 2005
Firstpage :
245
Lastpage :
250
Abstract :
Mechanobiology is indispensable to all living creatures ranging from bacteria to human beings because every living thing continually experiences mechanical stimuli, not only exogenous but also endogenous, and responds appropriately to these stimuli. At the cellular level, there are three major mechanical stresses, such as, stretch, shear stress and pressure. We have been intensively investigating systems to apply these mechanical environments to cells. Analysis of these responses is critical to understand the mechanisms and regulation of diverse physiological processes such as arterial and regulation, sensory perception, muscle development, and so on. Therefore, to study mechanobiology, we employed the polydimethysiloxane (PDMS) based technology, which is called soft lithography. In this article, I am going to focus on 3 major utilizations such as stretch chambers, microcontact printing, and microchannel.
Keywords :
biomechanics; biomedical materials; cellular biophysics; soft lithography; diverse physiological processes; mechanical stimuli; mechanical stresses; microcontact printing; muscle development; polydimethysiloxane based technology; sensory perception; soft lithography; stretch chambers; Blood flow; Cardiology; Cells (biology); Chemical technology; Dentistry; Microorganisms; Pharmaceuticals; Physiology; Soft lithography; Stress;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Micro-NanoMechatronics and Human Science, 2005 IEEE International Symposium on
Print_ISBN :
0-7803-9482-8
Type :
conf
DOI :
10.1109/MHS.2005.1589998
Filename :
1589998
Link To Document :
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