DocumentCode :
3206201
Title :
Synthesis, characterization and neurotoxicity of schiff bases derived from 1,8-diaminonaphthalene
Author :
Abu Bakar, Ahmad Fauzi ; Bahron, Hadariah ; Kassim, Karimah ; Zain, Mazatulikhma Mat
Author_Institution :
Department of Applied Chemistry, Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
fYear :
2010
fDate :
5-7 Dec. 2010
Firstpage :
1287
Lastpage :
1290
Abstract :
Six Schiff bases L1–L6 are successfully synthesized by reacting 1,8-diaminonaphthalene with aldehyde and ketone derivatives in the ratio of 1∶2 (amine: aldehyde / ketone). The Schiff bases are characterized using various physical and spectral techniques namely elemental analysis, IR spectroscopy, 1H NMR spectroscopy and melting point determination. The neurotoxicity of the compounds is evaluated using neuroblastoma SH-SY5Y cell lines at which they are indicated to be non-toxic.
Keywords :
Color; Compounds; Ethanol; Metals; Nuclear magnetic resonance; Protons; Spectroscopy; 1,8-diaminonaphthalene; Schiff base; neurotoxicity;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Science and Social Research (CSSR), 2010 International Conference on
Conference_Location :
Kuala Lumpur, Malaysia
Print_ISBN :
978-1-4244-8987-9
Type :
conf
DOI :
10.1109/CSSR.2010.5773736
Filename :
5773736
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=3206201
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