• DocumentCode
    3206201
  • Title

    Synthesis, characterization and neurotoxicity of schiff bases derived from 1,8-diaminonaphthalene

  • Author

    Abu Bakar, Ahmad Fauzi ; Bahron, Hadariah ; Kassim, Karimah ; Zain, Mazatulikhma Mat

  • Author_Institution
    Department of Applied Chemistry, Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
  • fYear
    2010
  • fDate
    5-7 Dec. 2010
  • Firstpage
    1287
  • Lastpage
    1290
  • Abstract
    Six Schiff bases L1–L6 are successfully synthesized by reacting 1,8-diaminonaphthalene with aldehyde and ketone derivatives in the ratio of 1∶2 (amine: aldehyde / ketone). The Schiff bases are characterized using various physical and spectral techniques namely elemental analysis, IR spectroscopy, 1H NMR spectroscopy and melting point determination. The neurotoxicity of the compounds is evaluated using neuroblastoma SH-SY5Y cell lines at which they are indicated to be non-toxic.
  • Keywords
    Color; Compounds; Ethanol; Metals; Nuclear magnetic resonance; Protons; Spectroscopy; 1,8-diaminonaphthalene; Schiff base; neurotoxicity;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Science and Social Research (CSSR), 2010 International Conference on
  • Conference_Location
    Kuala Lumpur, Malaysia
  • Print_ISBN
    978-1-4244-8987-9
  • Type

    conf

  • DOI
    10.1109/CSSR.2010.5773736
  • Filename
    5773736
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3206201