Nanodome sensor tubing for monitoring of intravenous drug infusion and metabolites

Author

Choi, Charles J. ; Wu, Hsin-Yu ; Weyhenmeyer, Jonathan ; George, Sherine ; Cunningham, Brian T.

Author_Institution

Electr. & Comput. Eng. Dept., Univ. of Illinois at Urbana-Champaign, Urbana, IL, USA

fYear

2011

fDate

15-18 Aug. 2011

Firstpage

161

Lastpage

165

Abstract

Continuous monitoring of fluids in medical tubing is desired for point-of-care clinical diagnostics. In this work, we incorporate a nanostructured surface-enhanced Raman scattering (SERS) sensor into flexible tubing commonly used for intravenous drug delivery and urinary catheters. We investigate the detection of promethazine (pain medication) and urea (common metabolite found in urine) as model systems for continuous in-line monitoring.

Keywords

catheters; drug delivery systems; drugs; nanosensors; optical sensors; patient diagnosis; patient monitoring; surface enhanced Raman scattering; SERS; continuous in-line monitoring; flexible tubing; intravenous drug delivery; intravenous drug infusion monitoring; metabolites; nanodome sensor tubing; nanostructured surface-enhanced Raman scattering sensor; pain medication; point-of-care clinical diagnostics; promethazine; urea; urinary catheters; Drugs; Fluids; Monitoring; Raman scattering; Real time systems; Sea measurements; Surface treatment;

fLanguage

English

Publisher

ieee

Conference_Titel

Nanotechnology (IEEE-NANO), 2011 11th IEEE Conference on

Conference_Location

Portland, OR

ISSN

1944-9399

Print_ISBN

978-1-4577-1514-3

Electronic_ISBN

1944-9399

Type

conf

DOI

10.1109/NANO.2011.6144316

Filename

6144316