Abstract :
Summary form only given. Nanotechnology has recently been applied to a wide range of biological systems. In particular, there is a current push to examine the interface between the biological world and micro/nano-scale systems. In this paper, the author presents ongoing work in microfluidics, biosensors, and nano-bio interfaces. Specific topics are included in the development of a DNA-based, microfluidic detection system and its use for both pathogen identification and forensic DNA analysis. In addition, the author covers current studies in magnetic-microfluidic integration, bacterial quorum sensing, bacterial adhesion, and novel optical detection systems. Some of the unique biological considerations for these systems are discussed, as well as issues relating to device fabrication and testing.
Keywords :
DNA; bioMEMS; biosensors; microfluidics; nanobiotechnology; DNA-based system; bacterial adhesion; bacterial quorum sensing; biosensors; forensic DNA analysis; magnetic-microfluidic integration; microbiological systems; microfluidic detection system; nanobio interfaces; nanobiological systems; nanotechnology; optical detection systems; pathogen identification; Biological systems; Biosensors; DNA; Forensics; Magnetic analysis; Microfluidics; Microorganisms; Nanobioscience; Nanotechnology; Pathogens;