Reconstruction of gated cardiac SPECT using DFT basis functions

Gated cardiac single photon emission computed tomography (SPECT) is an important diagnostic tool for evaluating both myocardial perfusion and ventricular function. However, it often suffers from increased noise due to gating. In this paper we explore the use of Fourier harmonic basis functions to model the time activities across the different gates, aiming to exploit the periodicity of cardiac beating. The gated frames are reconstructed through estimation in the frequency domain along the gate dimension. We demonstrate this approach by simulating gated Tc-99m labeled sestamibi imaging based on the NURBS- based cardiac-torso (NCAT) phantom.