Title :
Protein microarray chip with embedded microchannels
Author :
Tseng, Fan-Gang ; Chen, Y.F. ; Ho, C.E. ; Su, C.J. ; Chen, M.H. ; Lin, S.C. ; Huang, H.M. ; Chieng, C.C.
Author_Institution :
Eng. & Syst. Sci. Dept., Nat. Tsing Hua Univ., Hsinchu, Taiwan
Abstract :
The paper proposes and demonstrates a novel protein microarray chip with an embedded microchannel array for the delivery of protein separately. This chip system is applicable to high throughput disease diagnosis and drug screening. Demonstration in spot formations by the novel design using MEMS technology and characterization of the spot-forming process by numerical simulations are performed to illustrate the feasibility and the advantages of the presented design.
Keywords :
biosensors; integrated circuit design; integrated circuit technology; micromechanical devices; proteins; MEMS technology; embedded microchannel array; high throughput disease diagnosis; high throughput drug screening; micro-bio-reaction chip; micro-filling chip; microcontact printing; microfluidic channels; microstamper chip; microstamping; protein microarray chip design; spot formation; Equations; Filling; Microchannel; Numerical simulation; Printing; Protein engineering; Reservoirs; Systems engineering and theory; Testing; Throughput;
Conference_Titel :
Solid-State and Integrated Circuits Technology, 2004. Proceedings. 7th International Conference on
Print_ISBN :
0-7803-8511-X
DOI :
10.1109/ICSICT.2004.1435176