Rapid cholesterol detection by functionalized carbon nanotube based electrochemical sensor on flow injection microfluidic chip

Author

Wisitsoraat, A. ; Sritongkham, P. ; Karuwan, C. ; Phokharatkul, D. ; Maturos, T. ; Tuantranont, A.

Author_Institution

Nat. Electron. & Comput. Technol. Center, Pathumthani, Thailand

fYear

2009

fDate

25-28 Oct. 2009

Firstpage

1776

Lastpage

1779

Abstract

In this work, CNTs electrochemical electrode has been integrated on a flow injection based microfluidic chip for detection of cholesterol (CHO). Metal electrodes were deposited and CNTs were grown on a glass substrate by sputtering and chemical vapor deposition at low temperature. Polydimethylsiloxane microfluidic componet was then bonded on substrate. Cholesterol oxidase/potassium hexacyanoferrate were immobilized by polyvinyl alcohol using in-channel flow processing. Cholesterol detections were made by flow injection analysis and fast response time and high sensitivity have been achieved with high throughput of more than 100 samples per hour.

Keywords

bioMEMS; biochemistry; biomedical electrodes; biomedical measurement; carbon nanotubes; electrochemical electrodes; electrochemical sensors; lab-on-a-chip; microfluidics; nanotube devices; polymers; C; CNT electrochemical electrode; carbon nanotube; chemical vapor deposition; cholesterol oxidase; flow injection microfluidic chip; functionalised CNT based electrochemical sensor; in channel flow processing; metal electrodes; polydimethylsiloxane microfluidic component; polyvinyl alcohol; potassium hexacyanoferrate; rapid cholesterol detection; sputtering; Bonding; Carbon nanotubes; Chemical sensors; Chemical vapor deposition; Delay; Electrodes; Glass; Microfluidics; Sputtering; Temperature sensors;

fLanguage

English

Publisher

ieee

Conference_Titel

Sensors, 2009 IEEE

Conference_Location

Christchurch

ISSN

1930-0395

Print_ISBN

978-1-4244-4548-6

Electronic_ISBN

1930-0395

Type

conf

DOI

10.1109/ICSENS.2009.5398459

Filename

5398459