A multiscale deformable model for extracting complex surfaces from volume images

Deformable surface models are an attractive method for segmenting the three-dimensional shapes of complex anatomic structures in volumetric medical images. Despite the success of this approach, several problems remain. In this paper, we propose a multiscale deformable surface model with non-intersection constraint forces that successfully addresses three significant problems-sensitivity to model initialization, difficulties in dealing with severe object concavities, and model self-intersection. The first two problems are addressed by the multiscale scheme, which progressively resamples the triangulated, deformable surface model both globally and locally, matching its resolution to the levels of a volume image pyramid. We address the third problem by including a non-intersection constraint force among the customary internal and external forces in the physics-based formulation. We apply our new deformable surface model to the challenging task of extracting brain cortical surfaces