Position sensing of cells in diagnostic test systems by impedance measurement

Author

Thielecke, Hagen ; Stieglitz, Thomas ; Ruf, Hans Heinrich

Author_Institution

Fraunhofer Inst. for Biomed. Eng., St. Ingbert, Germany

Volume

2

fYear

1999

fDate

36434

Abstract

In cell-based biosensors which are used in test systems it is advantageous to position cells in array structures. Here, cells are positioned by hydrodynamic flow in microfabricated array structures on suction micro-holes with ring electrodes. The electrode impedance is measured to investigate if the positioning of cells can be electrically monitored. It is shown that hydrodynamic positioning of cells can be monitored by impedance measurement

Keywords

biocontrol; biosensors; electric impedance measurement; microelectrodes; microfluidics; micropositioning; position measurement; cell-based biosensors; diagnostic test systems; hydrodynamic flow; hydrodynamic positioning; impedance measurement; microfabricated array structures; position sensing of cells; ring electrodes; suction micro-holes; Electrodes; Frequency; Hydrodynamics; Impedance measurement; Monitoring; Position measurement; Sensor arrays; Sensor systems; Substrates; System testing;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.804004

Filename

804004