Title :
Modification of the RRM model using wavelets transform and ionisation constant to predict protein active sites
Author :
Cosic, Irena ; Fang, Qiang ; Pirogova, Elena
Author_Institution :
Dept. of Electr. & Comput. Syst. Eng., Monash Univ., Clayton, Vic., Australia
Abstract :
The resonant recognition model (RRM) which utilises the Fourier transform on the numerical representation of protein sequences obtained by representing each amino acid by an electron-ion interaction potential, has been shown useful in predicting the key amino acids for a protein sequence. Here, the authors discuss the modification of this model using ionisation constant to represent a protein sequence as a numerical series and continuous wavelet transform to predict active regions in the protein
Keywords :
Fourier transforms; ionisation; molecular biophysics; physiological models; proteins; wavelet transforms; RRM model modification; electron-ion interaction potential; ionisation constant; key amino acids prediction; numerical representation; protein active sites prediction; protein sequences; Amino acids; Continuous wavelet transforms; Fourier transforms; Ionization; Mice; Predictive models; Protein engineering; Protein sequence; Resonance; Wavelet transforms;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.804381