Proline-Based 2,5-Diketopiperazine Alkaloids from Starfish Pentaceraster chinensis

Author

Yan, Peng ; Liu, Yonghong

Author_Institution

Coll. of Chem. & Life Sci., Guangdong Univ. of Petrochem. Technol., Maoming, China

fYear

2011

fDate

10-12 May 2011

Firstpage

1

Lastpage

4

Abstract

Three known diketopiperazine alkaloids (1-3) were isolated from the EtOH extract of sea star Pentaceraster chinensis during our ongoing search for bioactive compounds from starfish. The structures were established on the basis of NMR data and comparison with those reported. Compounds 1-3 exhibited weak antibacterial activity against the Gram-positive bacterium Staphylococcus aureus, and compound 3 still showed weak antibacterial activity against the Gram-negative bacterium Escherichia coli in vitro.

Keywords

DNA; antibacterial activity; biochemistry; cellular biophysics; microorganisms; molecular biophysics; molecular configurations; proteins; Escherichia coli; EtOH extract; Gram-positive bacterium; NMR data; Staphylococcus aureus; antibacterial activity; bioactive compounds; diketopiperazine alkaloids; in vitro experiment; proline-based 2,5-diketopiperazine alkaloids; sea star Pentaceraster chinensis; starfish; Microorganisms; Nuclear magnetic resonance; Silicon compounds; Solids; Strain;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on

Conference_Location

Wuhan

ISSN

2151-7614

Print_ISBN

978-1-4244-5088-6

Type

conf

DOI

10.1109/icbbe.2011.5780168

Filename

5780168