DocumentCode
3320291
Title
Analytical Solution of Gene Regulatory Networks
Author
Gelenbe, Erol
Author_Institution
Imperial Coll. London, London
fYear
2007
fDate
23-26 July 2007
Firstpage
1
Lastpage
6
Abstract
We study gene regulatory networks that include the effect of multiple binary interactions, when various genes can activate or inhibit other genes, as well as of ternary interactions where two genes jointly affect the level of activity of a third gene. We also prove that Boolean identities for the activation state of a gene in terms of the activation level of another set of genes, can be represented, so that the overall probability of activation of any gene in the network can be computed in the presence of logical dependencies, and excitatory-inhibitory interactions between genes.
Keywords
genetic engineering; genetics; probability; Boolean identities; activation probability; excitatory-inhibitory interactions; gene regulatory networks; logical dependencies; multiple binary interactions; Biological information theory; Biological system modeling; Biology computing; Cells (biology); Computer networks; Continuous time systems; Negative feedback loops; Organisms; Proteins; Time factors;
fLanguage
English
Publisher
ieee
Conference_Titel
Fuzzy Systems Conference, 2007. FUZZ-IEEE 2007. IEEE International
Conference_Location
London
ISSN
1098-7584
Print_ISBN
1-4244-1209-9
Electronic_ISBN
1098-7584
Type
conf
DOI
10.1109/FUZZY.2007.4295674
Filename
4295674
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