Fluid movement in cortical bone in goats

Streaming potential is considered as one of the most important mechanisms to moderate the function of osteoblasts and osteocytes in bone growth, remodeling and fracture repair. The present study was designed to demonstrate the fluid flow pattern in the cortical bone matrix in an animal model using undecalcified histological techniques. Ferritin was observed in the interstitial compartment demonstrating as single or multiple halos around the Haversian canal for the first time. Irregular or incomplete ferritin halos indicated structural complexity of the osteons. Results suggested that the undecalcified technique might be used as a good method for future studies on cortical fluid flow qualitatively and quantitatively