Title :
A microprocessor based drug infusion control system employing a model reference adaptive control algorithm to regulate blood pressure in ICU patients
Author :
Hernandez, Leo ; Shankar, Ravi ; Pajunen, Grazyna A.
Author_Institution :
Dept. of Electr. & Comput. Eng., Florida Atlantic Univ., Boca Raton, FL, USA
Abstract :
The authors present an approach for adaptive control of blood pressure using sodium nitroprusside. A modified stochastic model reference adaptive control algorithm with a time-varying reference model is developed and used for this purpose. An automatic adjustment of the reference model is proposed to optimize the performance of the closed-loop system while meeting clinical constraints imposed on the infusion rate and the mean arterial pressure. The algorithm has been implemented in a microprocessor-based system. The system has been verified for proper functionality with the aid of a hardware patient model for a wide range of patient parameters
Keywords :
biocontrol; blood; closed loop systems; computerised control; model reference adaptive control systems; pressure control; stochastic systems; ICU patients; MRACS; biocontrol; blood pressure control; closed-loop system; computerised control; infusion rate; mean arterial pressure; microprocessor based drug infusion control system; model reference adaptive control; sodium nitroprusside; stochastic systems; time-varying reference model; Adaptive control; Arterial blood pressure; Biomedical monitoring; Blood pressure; Control system synthesis; Drugs; Microprocessors; Personnel; Pressure control; Programmable control;
Conference_Titel :
Southeastcon '89. Proceedings. Energy and Information Technologies in the Southeast., IEEE
Conference_Location :
Columbia, SC
DOI :
10.1109/SECON.1989.132625
