A diagnostic image system for assessing the severity of chronic liver disease

This paper describes a new ultrasonic scoring system based on the texture characteristics of ultrasonic liver images to generate an ultrasonic disease severity score that is highly correlated with the computer morphometry score obtained from fibrosis measurement of liver biopsy specimens. Essentially, the ultrasonic disease severity has great resemblance to the computer morphometry score in the statistical presentation. Therefore, the ultrasonic disease severity is defined mathematically referring to computer morphometry score as the scoring basis. As a result, the ultrasonic disease severity can faithfully reflect the disease progression of liver fibrosis. Promising results have been obtained in experimental studies and we are currently undergoing extensive clinical experiments