Development of a finite elements tool, for determining the mechanoelastic properties of the red blood cell

Author

Papaodysseus, C. ; Karabetsos, E. ; Kassis, K. ; Koukoutsis, E. ; Koutsouris, D.

Author_Institution

Dept. of Electr. & Comput. Eng., Nat. Tech. Univ. of Athens, Greece

Volume

5

fYear

1996

fDate

31 Oct-3 Nov 1996

Firstpage

2039

Abstract

In this paper a finite elements analysis tool is presented that has been developed in order to achieve a full simulation of the Red Blood Cell (RBC) motion and deformation in the circulation. Hence this tool is used to test the theoretically proposed constitutive relations that describe the mechanoelastic properties of the RBC. Consequently, it opens the way for finding the optimum constitutive relations that best fits the actual, observed in vivo RBC properties and its deformed RBC shapes. Here, the first results are shown, namely the RBC shape deformation during motion in free running plasma, for a specific set of constitutive equations concerning both the membrane and the cytoplasm too

Keywords

biomechanics; biomembranes; cellular biophysics; finite element analysis; haemorheology; physiological models; blood circulation; cell deformation; cell motion; cytoplasm; deformed RBC shapes; erythrocytes; finite elements tool; free running plasma; mechanoelastic properties determination; membrane; optimum constitutive relations; red blood cell; theoretically proposed constitutive relations; Analytical models; Deformable models; Finite element methods; In vivo; Mechanical factors; Motion analysis; Plasma properties; Red blood cells; Shape; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE

Conference_Location

Amsterdam

Print_ISBN

0-7803-3811-1

Type

conf

DOI

10.1109/IEMBS.1996.646418

Filename

646418