Scanning Magnetic Tunnel Junction Sensor for the Detection of Magnetically Labeled DNA Microarray

Author

Chan, Mei-Lin ; Jaramillo, Gerardo M. ; Horsley, David A.

Author_Institution

Univ. of California Davis, Davis

fYear

2007

fDate

10-14 June 2007

Firstpage

95

Lastpage

98

Abstract

In this paper, we introduce a magnetic scanning probe microscope based on a single magnetic tunnel junction (MTJ) sensor with a sensitivity of 4 V / mT to detect magnetic particles on DNA microarray. We demonstrate the direct measurement of the magnetic dipole fields associated with both micron size ferromagnetic nickel thin film patterns and monodispersed paramagnetic particles tagged to surface immobilized DNA by large area 2D scanning of sensor over the sample with scan speed of ~500 mu m/s.

Keywords

DNA; biosensors; ferromagnetic materials; magnetic sensors; magnetic tunnelling; ferromagnetic nickel thin film; magnetic dipole fields; magnetic scanning probe microscope; magnetically labeled DNA microarray; paramagnetic particles; scanning magnetic tunnel junction sensor; surface immobilized DNA; Area measurement; DNA; Magnetic field measurement; Magnetic force microscopy; Magnetic particles; Magnetic sensors; Magnetic tunneling; Probes; Thin film sensors; Velocity measurement; DNA microarray; Magnetic Particles; Magnetic Scanning Microscope; Magnetic Tunnel Junction (MTJ);

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems Conference, 2007. TRANSDUCERS 2007. International

Conference_Location

Lyon

Print_ISBN

1-4244-0842-3

Electronic_ISBN

1-4244-0842-3

Type

conf

DOI

10.1109/SENSOR.2007.4300080

Filename

4300080