The work of breathing in a nonlinear model of respiratory mechanics

Author

Athanasiades, A. ; Ghorbel, F. ; Clark, J.W., Jr. ; Niranjan, S.C. ; Liu, C.H. ; Zwischenberger, J.B. ; Bidani, A.

Author_Institution

Dept. of Mech. Eng., Rice Univ., Houston, TX, USA

Volume

5

fYear

1997

fDate

1997

Firstpage

2161

Abstract

Analytical expressions are derived for the work of breathing (WOB) and are subsequently evaluated for a typical pulmonary function laboratory test that includes tidal breathing, panting and the forced vital capacity maneuvers. The analysis is based on a nonlinear model of respiratory mechanics that successfully mimics information presented in the conventional Campbell diagram, which is often used to graphically estimate WOB. In addition, the model reveals the partitioning of elastic WOB among the collapsible airways and lung

Keywords

lung; muscle; physiological models; pneumodynamics; viscoelasticity; Campbell diagram; Lagrangian analysis; collapsible airways; compliant compartment; elastic work; forced vital capacity manoeuvres; lung tissue; muscular effort; nonlinear model; panting; partitioning; pleural pressure; pulmonary function laboratory test; respiratory mechanics; respiratory muscles; tidal breathing; viscous resistance; work of breathing; Biomedical computing; Biomedical engineering; Chemical engineering; Information analysis; Laboratories; Lungs; Mathematical model; Respiratory system; Surges; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE

Conference_Location

Chicago, IL

ISSN

1094-687X

Print_ISBN

0-7803-4262-3

Type

conf

DOI

10.1109/IEMBS.1997.758783

Filename

758783