Title :
A thalamus-to-cortex seizure pathway: a new coherence approach using sinusoidal modelling
Author :
Sherman, David L. ; Tsai, Yien Che ; Rossell, Lisa Ann ; Mirski, Marek A. ; Thakor, Nitish V.
Author_Institution :
Dept. of Biomed. Eng., Johns Hopkins Univ., Baltimore, MD, USA
fDate :
31 Oct-3 Nov 1996
Abstract :
A new method of measuring coherence between EEG channels is proposed for modeling the level of linear association during epileptic seizures. This method relies upon modelling the clonic seizure activity as a sum of sinusoids. The authors estimate contributions from correlated and uncorrelated sinusoidal components from information contained in auto- and cross-correlation matrices. Coherence estimates are formed from the ratio of correlated to total power. The authors illustrate the value of this method by examination of the strength of correlation between seizure EEG from specific thalamic nuclei and cortex in an animal model of generalized epilepsy
Keywords :
brain models; electroencephalography; medical signal processing; animal model; auto-correlation matrices; clonic seizure activity; coherence between EEG channels measurement method; coherence estimates; correlated to total power ratio; cross-correlation matrices; electrodiagnostics; generalized epilepsy; linear association level modelling; sinusoidal modelling; sinusoids sum; Biomedical measurements; Brain modeling; Coherence; Couplings; Electroencephalography; Epilepsy; Frequency estimation; Matrix decomposition; Parametric statistics; Signal processing;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.646506
