Development of water-soluble sono/photo-sensitive nanopartices for cancer treatment

Author

Meng, Yongde ; Zou, Chunpu ; Huang, Min ; Chen, Jie ; Xing, James

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of Alberta, Edmonton, AB, Canada

fYear

2010

fDate

May 30 2010-June 2 2010

Firstpage

1516

Lastpage

1519

Abstract

Sonodyanmic Therapy (SDT) is a new type of cancer therapy and has attracted lots of research attention recently. In this article, we present how nano-formulation helped SL052 to form a water soluble sono/photo-sensitize nanoparticle (SL052-NPs) for cancer treatment. The nanostructure formation encapsulates SL052 and greatly improves the SL052 physicochemical properties without modifying its chemical structure. Nano-formulation also helps SL052 to achieve deep-site cancer delivery, image function for diagnosis, and ultrasound or photo controlled localized cancer therapy.

Keywords

biomedical materials; cancer; nanobiotechnology; nanofabrication; nanoparticles; photodynamic therapy; ultrasonic therapy; SL052-NP; cancer therapy; deep-site cancer delivery; sonodyanmic therapy; water soluble sono/photo-sensitize nanoparticle; Absorption; Biomedical imaging; Cancer; Chemicals; Drugs; Medical treatment; Nanobioscience; Nanoparticles; SONOS devices; Ultrasonic imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Circuits and Systems (ISCAS), Proceedings of 2010 IEEE International Symposium on

Conference_Location

Paris

Print_ISBN

978-1-4244-5308-5

Electronic_ISBN

978-1-4244-5309-2

Type

conf

DOI

10.1109/ISCAS.2010.5537376

Filename

5537376