Title :
Performance comparison of low current measurement systems for biomedical applications
Author :
Kim, Dongsoo ; Tang, Wei ; Goldstein, Brian ; Weerakoon, Pujitha ; Montanaro, Hazael ; Martini, Berin ; Culurciello, Eugenio
Author_Institution :
Dept. of Electr. Eng., Yale Univ., New Haven, CT, USA
fDate :
May 30 2010-June 2 2010
Abstract :
In this paper, we report on the noise analysis of low current measurement systems for biomedical applications. We analyzed resistive feedback, capacitive feedback and current conveyor circuits for low current measurement systems. Detailed noise analysis are presented and matched with measurement data using a 0.5-μm fabrication process. Based on the theoretical analysis and the measurements, the capacitive feedback system provides better noise performance for the measurement of low current. The capacitive feedback is capable of measuring 700fA RMS at 10KHz sampling rate, whereas the resistive feedback provides 4pA and the current conveyor provides 600pA. This paper provides design guidelines to maximize the measurement performance of low current for biomedical instrumentation.
Keywords :
bioelectric phenomena; feedback; noise; biomedical application; capacitive feedback; current conveyor circuit; low current measurement system; noise performance; performance comparison; resistive feedback; Biomedical measurements; Circuit noise; Current measurement; DNA; Feedback; Immune system; Impedance; Integrated circuit measurements; Noise measurement; Performance analysis;
Conference_Titel :
Circuits and Systems (ISCAS), Proceedings of 2010 IEEE International Symposium on
Conference_Location :
Paris
Print_ISBN :
978-1-4244-5308-5
Electronic_ISBN :
978-1-4244-5309-2
DOI :
10.1109/ISCAS.2010.5537843