Title :
Investigation of EMF induced protein conformational changes using an optical assay
Author :
Liu, W. ; Cook, G.G. ; Barker, A.T. ; Coulton, L.A.
Author_Institution :
Dept. of Electron. & Electr. Eng., Univ. of Sheffield, Sheffield
Abstract :
Bovine serum albumin is exposed to a low frequency electric field and spectrofluorimetry then used as an assay for changes in protein structure. Any such changes occurring in analogous proteins may be biologically significant in-vivo. Oscillatory fluorescence variations synchronized with the electric field bursts are observed but the cause of these is unclear.
Keywords :
electric potential; electromagnetic fields; EMF induced protein conformational changes; bovine serum albumin; electric field bursts; electric fields; optical assay; oscillatory fluorescence variations; spectrofluorimetry; Antennas and propagation; Biomedical optical imaging; Bovine; Fluorescence; Frequency synchronization; Heating; Optical propagation; Physics; Protein engineering; Temperature;
Conference_Titel :
Antennas and Propagation Conference, 2008. LAPC 2008. Loughborough
Conference_Location :
Loughborough
Print_ISBN :
978-1-4244-1893-0
Electronic_ISBN :
978-1-4244-1894-7
DOI :
10.1109/LAPC.2008.4516893
