Title :
Parametric stability in a cellular oscillator
Author_Institution :
Sch. of Sci., Eng. & Technol., Pennsylvania State Univ., Middletown, PA, USA
Abstract :
A comprehensive neuromime realized in CMOS VLSI circuitry was used to reconstruct and parametrically test the cellular oscillator that gives rise to swimming motion in hirudo, the medicinal leech. Each subunit of the leech swim network consists of a number of embedded cyclic and reciprocal sub-oscillators. Tests on the two sub-oscillator types indicate that the cellular and environmental parameters to which they are most immune complement one another. Tests on an entire subunit of the leech network show that the overall stability of the network is attributable to the product of the stability of its sub-oscillators
Keywords :
CMOS analogue integrated circuits; VLSI; analogue processing circuits; biocontrol; bioelectric potentials; biomembrane transport; cell motility; circuit stability; neural chips; neurophysiology; oscillators; CMOS VLSI circuitry; cellular oscillator; comprehensive neuromime; embedded cyclic sub-oscillators; environmental parameters; hirudo; leech swim network; medicinal leech; postsynaptic cell membrane potential; presynaptic cell membrane potential; reciprocal sub-oscillators; sub-oscillator stability; swimming motion; Biomembranes; CMOS technology; Capacitors; Cells (biology); Circuit stability; Circuit testing; Fatigue; Oscillators; Radio control; Rhythm;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.579777