Title :
In-vivo ESR and EPR imaging
Author :
Berliner, Lawrence J. ; Fujii, Hirotada ; Wan, Xiaoming
Author_Institution :
Dept. of Chem., Ohio State Univ., Colombus, OH, USA
Abstract :
The authors are utilizing electron spin resonance (ESR) spectroscopy for noninvasive examination of living animals. Due to the intense interest in nitroxides as potential nuclear magnetic resonance (NMR) contrast agents (and built-in ESR imaging agents) they are studying the pharmacokinetics of nitroxides directly in vivo, as a probe of redox metabolism in various tissues. The results are also promising in assessing the feasibility for ESR imaging measurements at the tissue site of interest.<>
Keywords :
paramagnetic resonance; patient diagnosis; EPR imaging; ESR imaging; contrast agents; medical imaging; nitroxides; noninvasive examination; pharmacokinetics; redox metabolism; tissue site of interest;
Conference_Titel :
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location :
New Orleans, LA, USA
Print_ISBN :
0-7803-0785-2
DOI :
10.1109/IEMBS.1988.94576
