Title :
Microfluidic detection and analysis by integration of evanescent wave sensing with thermocapillary actuation
Author :
Valentino, J.P. ; Troian, S.M. ; Wagner, S.
Author_Institution :
Dept. of Electr. Eng., Princeton Univ., NJ, USA
fDate :
30 Jan.-3 Feb. 2005
Abstract :
An integrated system capable of microfluidic actuation, detection and sensing is described which combines evanescent wave sensing with thermocapillary manipulation. Liquid droplets or streams transported across the beam path of a planar thin film waveguide, which encapsulates the microheater array, induce attenuation of the propagating waveguide modes. The attenuated signal is used to monitor droplet location, dye concentration in aqueous solutions and reaction kinetics for enzymatic hydrolysis of the sugar X-galactose by beta-galactosidase.
Keywords :
biological techniques; biosensors; drops; fibre optic sensors; microactuators; microfluidics; micromanipulators; optical waveguides; beam path; beta-galactosidase; droplet location; dye concentration; enzymatic hydrolysis; evanescent wave sensing; liquid droplets; microfluidic actuation; microfluidic analysis; microfluidic detection; microheater array; planar thin film waveguide; reaction kinetics; sugar X-galactose; thermocapillary actuation; thermocapillary manipulation; Microfluidics; Optical films; Optical mixing; Optical planar waveguides; Optical refraction; Optical sensors; Optical surface waves; Optical variables control; Optical waveguides; Planar waveguides;
Conference_Titel :
Micro Electro Mechanical Systems, 2005. MEMS 2005. 18th IEEE International Conference on
Print_ISBN :
0-7803-8732-5
DOI :
10.1109/MEMSYS.2005.1454033
