Title :
Transfer impedance of awake rats measured by the forced oscillation technique
Author :
Oostveen, Ellie ; Zwart, Aart
Author_Institution :
Dept. of Biol. Toxicology, TNO-CIVO Toxicology & Nutrition Inst., Zeist, Netherlands
Abstract :
An instrument has been constructed to measure the respiratory transfer impedance of awake, restrained rats in the frequency range 20-200 Hz. The measured transfer impedance in normal rats is in agreement with the input impedance measured by A.C. Jackson and J.W. Watson (1982) between 20-90 Hz. The peak impedance which occurred between 100-120 Hz appears to be a very sensitive index for the lung function. After a single 4-hr exposure to ozone a transient response lasting about four weeks was observed during which the main changes occurred between 100 and 150 Hz.<>
Keywords :
biological techniques and instruments; lung; pneumodynamics; 20 to 200 Hz; forced oscillation; lung function; ozone; rats; respiratory transfer impedance;
Conference_Titel :
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location :
New Orleans, LA, USA
Print_ISBN :
0-7803-0785-2
DOI :
10.1109/IEMBS.1988.94861
